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摘要目的通过特定行为学测量的方法,如依赖症状计数、行为方法和冲动,研究性别能否调节长期禁欲的兴奋剂依赖性病人的灰质体积(GMV),并表征性别如何调节GMV。材料与方法本研究经科罗拉多机构伦理委员会批准并获得病人知情同意书。在该前瞻性、平行组的研究中,127例年龄和性别匹配的被试[68例对照(女28例,男40例)和59例兴奋剂依赖病人(女28例,男31例)]行颅脑3 T扰相梯度回波反转恢复T_1W MRI。影像利用基于体素的形态测量软件
Abstract Objective To investigate whether gender can modulate the gray matter volume (GMV) of stimulant-dependent patients with long-term abstinence, and to characterize how gender modulates GMV by means of specific behavioral measures such as dependence on symptom counts, behavioral methods, and impulses. Materials and Methods The study was approved by the Colorado Agency Ethics Committee and informed consent was obtained. In the prospective, parallel-group study, 127 age- and sex-matched subjects [68 controls (28 males and 40 females) and 59 doping-dependent patients (28 females and 31 males) T 3 W MRI was performed by 3 T scrambling gradient echo in brain. Images utilize voxel based morphometry software