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目的通过对近几年池州市出生缺陷监测资料进行分析,了解出生缺陷的发生及变化趋势,为制定出生缺陷的预防措施提供依据。方法对池州市2009年~2014年9家监测医院分娩的45 935例围产儿的出生缺陷监测资料进行了分析。结果共监测到围产儿出生缺陷276例,总发生率为6.01‰,发生率较高的出生缺陷依次为总唇裂、多指(趾)、外耳畸形和先天性心脏病,神经管畸形年发生率呈逐年下降趋势,出生缺陷发生率存在性别差异,男性(6.77‰)高于女性(5.19‰),经卡方检验,差异均有统计学意义(P<0.05)。结论应积极开展出生缺陷的三级预防,采取综合干预措施,减少出生缺陷的发生。
Objective To analyze the birth defect monitoring data in Chizhou City in recent years to understand the occurrence and change trend of birth defects and provide the basis for the prevention measures of birth defects. Methods The surveillance data of 45 935 perinatal births in 9 monitoring hospitals in Chizhou from 2009 to 2014 were analyzed. Results A total of 276 cases of perinatal birth defects were detected, with a total incidence of 6.01 ‰. The highest incidence of birth defects were total cleft lip, multiple digits (TOE), external ear deformity, congenital heart disease and annual incidence of neural tube defects There was a decreasing trend year by year. There was a gender difference in the incidence of birth defects, which was significantly higher in males (6.77 ‰) than in females (5.19 ‰). The chi square test showed significant differences (P <0.05). Conclusion The tertiary prevention of birth defects should be actively carried out and comprehensive interventions should be taken to reduce the incidence of birth defects.