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Ⅱ型(非胰岛素依赖型)糖尿病患者,大多数较肥胖,适用降低体重并促进糖代谢的药物。氟苯丙胺是食欲抑制剂,刺激中枢神经系统,减少间脑5-羟色胺的合成与贮存,使食欲减退,体重下降;并且对糖代谢有促进作用。用氟苯丙胺治疗一组Ⅱ型糖尿病,剂量60mg/d。患者体重平均超过正常48%左右,年龄29～61(平均48)岁。患病史达1年者17例,1～10年9例。初诊时都有糖尿病失代偿症状。6例有家族史。伴发病:慢性胆囊炎6例,高血压病11例,糖尿病性肾病和视网膜病2例。
Type II (non-insulin-dependent) patients with diabetes, the majority of more obese, apply to reduce weight and promote glucose metabolism drugs. Fenfluramine is an appetite suppressant, stimulating the central nervous system, reducing the synthesis and storage of mesencephalic serotonin, so that loss of appetite, weight loss; and promote glucose metabolism. A group of type II diabetes was treated with fenfluramine at a dose of 60 mg / d. The average weight of patients over the normal 48%, aged 29 to 61 (average 48) years old. 17 cases had a history of 1 year and 9 cases between 1 and 10 years. Diabetes mellitus symptoms are present at first visit. 6 cases had a family history. Incidence: chronic cholecystitis in 6 cases, hypertension in 11 cases, diabetic nephropathy and retinopathy in 2 cases.