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目的:观察降纤酶治疗急性脑梗死的临床疗效。方法:将60例急性脑梗死患者随机分为治疗组和对照组,其中治疗组32例,对照组28例。对照组给予常规治疗,治疗组在常规治疗的基础上给予降纤酶10U加入生理盐水100ml静滴,1次/d,连用3d,在发病24h内开始治疗。观察两组治疗14d后疗效。结果:治疗组总有效率为87.5%,对照组总有效率为64.3%,两组比较差异有统计学意义(P<0.05)。结论:急性脑梗死患者应用降纤酶治疗是安全有效的方法,值得基层医院推广应用。
Objective: To observe the clinical efficacy of defibrase in the treatment of acute cerebral infarction. Methods: Sixty patients with acute cerebral infarction were randomly divided into treatment group and control group, including 32 in treatment group and 28 in control group. The control group was given routine treatment. The treatment group was given 10U defibrase (10U) intravenously with 100ml normal saline once a day for three days. The treatment group started treatment within 24 hours after the onset of disease. After 14 days of treatment, the curative effect was observed. Results: The total effective rate was 87.5% in the treatment group and 64.3% in the control group. There was significant difference between the two groups (P <0.05). Conclusion: The application of defibrase in patients with acute cerebral infarction is a safe and effective method, which is worth popularizing and applying in primary hospitals.