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目的:研究尼卡地平对老年高血压患者术毕拔管反应的影响。方法:48例老年高血压病患者,术毕随机分为硝酸甘油组和尼卡地平组,分别静脉注射硝酸甘油与尼卡地平,拔管后停止。记录用药前、吸痰时、拔管即刻,拔管后1、5、10 min的心率、血压、心率-收缩压乘积。结果:两组在拔管后1、5 min时血压和心率差异有统计学意义。结论:尼卡地平可有效预防老年高血压患者气管拔管时血压升高、心率增快。
Objective: To study the effect of nicardipine on extubation response in elderly hypertensive patients. Methods: Forty-eight elderly patients with essential hypertension were randomly divided into nitroglycerin group and nicardipine group. Nitroglycerin and nicardipine were injected intravenously and stopped after extubation. Record medication, suction, immediately extubation, 1,5,10 min after extubation heart rate, blood pressure, heart rate - systolic blood pressure product. Results: There was a significant difference in blood pressure and heart rate between the two groups at 1,5 min after extubation. Conclusion: Nicardipine is effective in preventing hypertension and increasing heart rate during tracheal extubation in elderly hypertensive patients.