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目的:探讨24周不同方式的规律运动对肥胖绝经妇女血清脂联素水平和胰岛素抵抗的影响。方法:将36名受试者随机分成有氧练习组(AE)、有氧练习结合抗阻力练习组(AE+RE)及对照组(CON),进行24周的实验,实验前后测量身体形态指标、空腹血糖(FPG)、血脂、胰岛素(FINS)及血清脂联素(ADI),并计算胰岛素抵抗指数(HOMA-IR)。结果:两运动组的体脂含量(FM)、体脂百分比(%F)、体重、腰臀比(WHR)、FPG、FINS和HOMA-IR水平均较实验前显著下降;血清ADI水平呈上升趋势(AE组上升7.7%,AE+RE组上升17.2%),但无统计学意义。实验后两运动组各指标间无显著性差异。按照实验后体重变化分组,体重下降大于3kg的组脂联素变化水平显著高于未下降组。结论:24周不同方式运动显著改善胰岛素抵抗状态,但对脂联素水平无显著影响;脂联素水平上升不是运动导致的胰岛素抵抗改善的必要条件。
Objective: To investigate the effect of 24-week regular exercise on serum adiponectin level and insulin resistance in overweight and postmenopausal women. Methods: 36 subjects were randomly divided into aerobic exercise group (AE), aerobic exercise combined with anti-resistance exercise group (AE + RE) and control group (CON) for 24 weeks. Before and after the experiment, body shape index , Fasting blood glucose (FPG), lipids, insulin (FINS) and serum adiponectin (ADI), and calculate the insulin resistance index (HOMA-IR). Results: The levels of body fat (F), body fat (% F), body weight, WHR, FPG, FINS and HOMA-IR in the two exercise groups decreased significantly compared with those before the experiment. Trend (AE group increased 7.7%, AE + RE group increased 17.2%), but not statistically significant. There was no significant difference between the two exercise groups after the experiment. In accordance with the experimental weight changes grouping, body weight loss greater than 3kg group adiponectin levels were significantly higher than the non-descending group. CONCLUSIONS: Exercise at 24 weeks significantly improved insulin resistance with no significant effect on adiponectin levels; increased adiponectin levels were not a necessary condition for exercise-induced improvements in insulin resistance.