目的　观察内镜注射治疗联用西咪替丁及单用西咪替丁静脉注射 ,对消化性溃疡活动性出血患者的疗效。方法　采用随机对照的方法。把 48例内镜下有活动性出血的消化性溃疡患者 ,随机分为 2组 ,第I组内镜注射止血药联用西咪替丁 40 0mg ,Q12h静脉注射 ,疗程 5d ;第Ⅱ组单用西咪替丁 40 0mg ,Q12h静脉注射 ,疗程 5d。治疗期间观察患者的止血时间、输血量、再出血情况及住院时间。结果　第I组患者止血时间、输血量、再出血率、手术率和住院时间较第Ⅱ组显著缩短(或下降 ) ,两组死亡率无显著差异。结论　内镜注射治疗联用西咪替丁 40 0mg,Q12h静脉注射疗效较好 Objective To observe the effect of endoscopic injection combined with cimetidine and intravenous cimetidine intravenous injection on patients with active peptic ulcer bleeding. Methods Randomized controlled methods. 48 cases of peptic ulcer patients with active bleeding under endoscopy were randomly divided into two groups, group I endoscopic injection hemostatic combined with cimetidine 40 0mg, Q12h intravenous injection, the treatment of 5d; Cimetidine 40 0mg, Q12h intravenous injection, treatment 5d. Hemostatic time, blood transfusion, rebleeding and hospital stay were observed during treatment. Results The bleeding time, blood transfusion, rebleeding rate, operation rate and length of stay in Group I patients were significantly shorter (or decreased) than those in Group II patients. There was no significant difference in mortality between the two groups. Conclusion Endoscopic injection combined with cimetidine 40 0mg, Q12h intravenous injection is better