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26例新发2型糖尿病(T2DM)患者给予2周甘精胰岛素强化治疗(三餐配合使用速效胰岛素);治疗前后测定空腹血糖(FPG)、空腹胰岛素(FINS),并计算IAI、胰岛素抵抗指数(HOMA-IR)。结果IAI明显增加,HOMA-IR显著改善。结论对新发T2DM,胰岛素强化治疗可以快速、稳定控制血糖,改善胰岛B细胞功能和IAI。
Twenty-six patients with newly diagnosed type 2 diabetes mellitus (T2DM) were given insulin glargine for 2 weeks (fasting insulin for three meals), fasting blood glucose (FPG) and fasting insulin (FINS) before and after treatment. IAI, insulin resistance index (HOMA-IR). Results IAI increased significantly, HOMA-IR significantly improved. Conclusions For newly diagnosed T2DM, intensive insulin therapy can rapidly and stably control blood glucose, improve islet B cell function and IAI.