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目的 分析麻风可疑症状与确诊麻风的关系,促进麻风病例的早期发现.方法 对深圳市2012-2016年报告的271例可疑麻风病例进行整理分析,内容包括社会人口学特征、病程、麻风可疑临床症状、确诊结果,利用Logistic回归方法建立对于确诊结果的预测模型.结果 皮肤出现红斑白斑、斑块、结节不痒不痛,久治不愈(OR=173.46,95％ CI:12.54 ～2 398.55);面部或耳垂出现肿胀或结节肿块,或四肢、躯干出现中央有“免疫区”环状皮损(OR=566.97,95％ CI:4.98 ～64 577.82);酒醉面容,眉毛稀疏脱落(OR=106.85,95％ CI:8.74 ～1 305.80);四肢局部皮肤感觉麻木或麻刺感或皮肤无汗(OR=55.06,95％ CI:8.01～379.58),符合以上症状与体征者更倾向被确诊为麻风.回归模型灵敏度76.47％、特异度99.21％、总正确率为97.79％,回归模型具有统计学意义(P=0.00).结论 医务人员应注重对麻风可疑症状的掌握,并以此为基础探索性地利用回归模型开展疑似麻风病例发现工作,对于麻风早发现、早诊断、早治疗具有重要意义.“,”Objective To analysis the relationship between suspicious symptoms and confirmed leprosy,and to make early diagnosis of the leprosy.Methods Data of 271 suspicious leprosy cases,including the social demographics,disease course,suspicious symptoms,and confirmed diagnosis,reported in 2012-2016 were analyzed.Logistic regression method was used to establish the predicted model of the confirmed diagnosis.Results The suspicious leprosy patients with the following symptoms were more likely to be diagnosed as leprosy:erythema,depigmentation,asymptomatic nodules which did not respond to conventional treatment (OR =173.46,95％ CI:12.54 ～2 398.55);swelling or lump on the face or earlobe,annular lesions on the limbs and trunk (OR =566.97,95 ％ CI:4.98 ～ 64 577.82);drunken face,sparse eyebrows (OR =106.85,95％ CI:8.74 ～ 1 305.80);numbness or tingling sensation of the skin (OR =55.06,95 ％ CI:8.01 ～ 379.58),and anhidrosis.Sensitivity of the regression model was 76.47％,with specificity of 99.21％.Total correction rates were 97.79％.Overall regression model had statistically significant (P =0.00).Conclusion The doctors should pay more attention to the suspicious symptoms of leprosy.The regression model can be used to facilitate earlydiagnosis and treatment of leprosy.