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肾上腺皮质的主要盐皮质激素(MCH)是11-去氧皮质酮和醛固酮。11-去氧皮质酮(DOC)在正常浓度时是与球蛋白结合的,潴钠排钾作用较弱,因而在整个盐皮质激素活性中只占很少部分。而醛固酮是游离的,故生理活性较强。本文讨论血压异常和钾代谢疾患中醛固酮分泌的变化。
The main mineralocorticoid (MCH) of the adrenal cortex is 11-deoxycorticosterone and aldosterone. 11-Deoxycorticosterone (DOC), which binds to globulin at normal concentrations, has a weak potassium retention role and therefore accounts for only a small fraction of the total mineralocorticoid activity. The aldosterone is free, so strong physiological activity. This article discusses the changes in aldosterone secretion in abnormal blood pressure and potassium metabolism disorders.