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的探讨伽玛刀对松果体区肿瘤治疗的有效性。方法25例共31个病灶,治疗前肿瘤平均体积为54cm3(0092~293cm3);KPS平均为7923分(50~100分);射点数1~8个(平均42个);周边剂量10~225Gy(平均1486Gy);周边剂量曲线30%~90%(平均439%);中心剂量1444~5625Gy(平均3618Gy)。结果19个月内有14例获得随访,平均随访期为55个月,治疗后平均肿瘤体积缩小至44cm3(0~267cm3)。治疗后肿瘤体积缩小者临床症状有明显好转或改善,KPS平均为8692分(50~100分)。结论定位诊断明确的松果体区占位病变,如果其体积在伽玛刀治疗的允许范围内,首选伽玛刀治疗是明智的,可获得良好的预后。
Explore the effectiveness of Gamma Knife for the treatment of pineal region tumors. Methods A total of 31 lesions were performed in 25 patients. The average volume of tumor before treatment was 54cm3 (0092~293cm3); the average KPS was 7923 (50~100); the number of shot points was 1~8 (average 4). 2); Peripheral dose 10 to 22 5 Gy (average 14 86 Gy); Peripheral dose curve 30% to 90% (average 43 9%); Central dose 14 44 to 56 25 Gy (mean 36 18 Gy) . Results Fourteen patients were followed up within 19 months. The average follow-up period was 5 to 5 months. After treatment, the average tumor size was reduced to 44cm3 (0 to 267cm3). After treatment, the clinical symptoms of tumors with reduced tumor volume were significantly improved or improved. The mean KPS was 86.92 points (50 to 100 points). Conclusions Locating lesions clearly identified in the pineal region, if the volume is within the allowable range of gamma knife treatment, the preferred gamma knife treatment is wise and can achieve a good prognosis.