研究表明单核巨噬细胞系统的功能受急性及慢性接触镉的影响。本实验旨在进一步阐明长期接触低剂量镉后免疫功能改变的特征及中止镉接触后,免疫功能的改变是否可逆。实验用CBA/H雄性小鼠,自由饮水,水中含镉量300ppm,持续一年。在此期间内不断测定绵羊红细胞(E)消除率和迟发型变态反应,以了解镉对单核巨噬细胞及T细胞功能 Studies have shown that the function of mononuclear macrophage system is affected by acute and chronic exposure to cadmium. This experiment aims to further clarify the long-term exposure to low doses of cadmium after the immune function changes and the suspension of cadmium exposure, the immune function is reversible. Experimental CBA / H male mice, free access to water, water cadmium content of 300ppm, for one year. Sheep red blood cell (E) elimination rate and delayed type allergy were measured continuously during this period to understand the effect of cadmium on monocyte-macrophage and T cell function