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目的：研究观察对消化内科患者采用无痛胃镜诊治的临床应用价值。方法：选取2010年1月至2012年12月期间在我院消化内科收治的310例采用无痛胃镜治疗的患者作为研究对象，将其随机分为试验组与对照组，每组各155例。给予对照组患者进行胃肠道检查治疗，试验组患者先予以麻醉镇痛，再对采用无痛胃镜进行治疗。结果：治疗组患者中总有效率为98.06%，对照组患者中总有效率为58.06%，两组比较，有统计学意义（P＜0.05）。治疗组患者中发生疼痛9例不良反应，对照组患者中发生疼痛87例，两组比较，差异均有统计学意义（P均＜0.05）。结论：采用无痛胃镜诊治消化内科患者有较好的临床疗效，安全性高，值得在临床工作中予以推广及应用。“,”Objective: To study the observation of Gastroenterology patients with painless gastroscopy diagnosis and treatment of clinical value. Methods: April 2009 to October 2012, 310 cases the Gastroenterology admitted in our hospital painless gastroscopy treatment of patients as research subjects, and they were randomly divided into experimental group and control group, n=155 cases. Given to the control group patients for examination and treatment of the gastrointestinal tract, the experimental group patients to be narcotic analgesic treatment for painless gastroscopy. Results: In patients treated with total effective rate of 98.06%in the control group of patients total effective rate was 58.06%, the two groups was statisticaly significant (P <0.05). Pain in 9 cases of adverse reactions in patients treated with pain in 87 cases in the control group patients, the two groups, the differences were statisticaly significant (P<0.05). Conclusion: The diagnosis and treatment of painless gastroscopy Gastroenterology patients with better clinical efficacy, safety, worth to be promoted and applied in clinical work.