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1病例资料患者,女,67岁。因“发作性喘息伴双下肢麻木、皮肤多发溃疡7年,加重2 d”于2009年11月23日入院。患者7年前无明显诱因出现发作性喘息,偶咳少量白痰,无咳黄脓痰,无发热及盗汗,按“支气管哮喘急性发作”处理可明显缓解,未正规按哮喘长期规律用药,前4年共大发作2次(约2年1次),后3年每年大发作1次,近1年大发作2次。7年期间伴发双下肢无力、发麻、针刺感,四肢皮肤多部位反复并发溃疡、红肿,伴视物模糊。无咳粉红色痰、胸闷、
1 case information patients, female, 67 years old. Because of “episodic wheezing with double lower extremity numbness, multiple skin ulcers for 7 years, increased 2 d ” on November 23, 2009 admission. 7 years ago, there was no obvious incentive for patients with episodic wheezing, even cough a small amount of white sputum, no cough yellow purulent sputum, no fever and night sweats, according to “acute exacerbation of bronchial asthma” can be significantly relieved, not formally according to the long-term asthma medication , The first 4 years a total of 2 episodes (about 2 years 1), 3 years after the annual episode 1, nearly 1 year episode 2 times. During 7 years accompanied by weakness of both lower extremities, numbness, acupuncture, limbs and multiple parts of the skin repeated ulcers, redness, with blurred vision. No cough pink sputum, chest tightness,