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本文研究材料为有重型病毒性肝炎临床表现的尸检病例30例。对其临床资料、尸检记录、肝脏的大体和组织切片标本作了详细的研究。病例中男性23例,女性7例。其平均年龄为27.9岁,最小者8岁,最大者57岁。其中4例儿童平均年龄为9.5岁。其病程均在一个月以上,但其长短甚不一致,长者可达96个月之久。病例中至少有73.3％在发病前曾患过急性肝炎或(和)慢性活动性肝炎。故其临床经过同突然发作和病程短促的暴发性肝炎迥然不同。 这30例的肝脏病理变化可分为亚急性坏死性肝炎(Ⅰ型)、坏死-增生性肝炎(Ⅱ型)、肝硬化前期性肝炎(Ⅲ型)和肝硬化性肝炎(Ⅳ型)四种类型。这四种病理类型,既各有其特征又有相互重叠之处,按其发展顺序,能够反映亚急性肝坏死演变为肝硬化的过程中既有区别又有联系的四个不同的阶段。
In this paper, 30 cases of autopsy cases with clinical manifestations of severe viral hepatitis were studied. The clinical data, autopsy records, the liver and tissue specimens in general made a detailed study. In the case of 23 males and 7 females. The average age is 27.9 years old, the youngest is 8 years old, the largest is 57 years old. The average age of 4 children was 9.5 years old. Its duration is more than a month, but its length is very inconsistent, the elderly up to 96 months old. At least 73.3% of the cases had had acute hepatitis or (and) chronic active hepatitis before onset. Therefore, its clinical experience with sudden onset and short duration of fulminant hepatitis is very different. These 30 cases of liver pathological changes can be divided into subacute necrotizing hepatitis (type Ⅰ), necrosis - proliferative hepatitis (type Ⅱ), cirrhosis of the liver (Ⅲ) and cirrhosis of the liver (Ⅳ) four Types of. The four pathological types have their own characteristics and overlap each other, according to the sequence of development, can reflect the evolution of subacute liver necrosis into cirrhosis of the process of both the distinction between the four different stages of contact.