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对于原发性肺癌的治疗方法除小细胞未分化癌外一般均优先考虑外科手术。然而由于肺癌诊断明确时已大部分(80%)病例是不能手术切除,而放射治疗与化学治疗的病例疗效亦差,前者五年生存率在5%左右,后者更差,因此必须研究新的方法来提高疗效,现介绍日本近年对原发性肺癌所进行的临床治疗进展。一、肺癌外科手术前,手术中局部区域化疗及术后长期间歇化疗。肺癌的化疗已为普遍所用,为了防止手术中癌细胞的血行转移,提高疗效,有人对肺癌进行支气管动脉造影,发现在病灶部位有多数不规则的新生血管增生即所谓肿瘤染色(Tumor stain),在大多数病例中可看到支气管动脉的血流增加和肿瘤组织的造影剂漏出血管外的形象,造影剂的血管外漏
The treatment of primary lung cancer is generally given priority to surgery except small cell undifferentiated cancer. However, due to the clear diagnosis of lung cancer, most of the cases (80%) are inoperable, and the radiotherapy and chemotherapy treatments are also in poor efficacy. The former has a five-year survival rate of about 5%, and the latter is even worse. Therefore, new studies must be conducted. In order to improve the therapeutic effect, we present the progress of clinical treatment of primary lung cancer in Japan in recent years. First, before surgery for lung cancer, local chemotherapy and long-term intermittent chemotherapy after surgery. The chemotherapy of lung cancer has been widely used. In order to prevent the metastasis of cancer cells during surgery and improve the curative effect, bronchial arterial angiography has been performed on lung cancer and it has been found that there are many irregular neovascular hyperplasias (Tumor stains) at the lesion site. In most cases, an increase in the blood flow of the bronchial artery and an image of the contrast agent in the tumor tissue outside the blood vessel can be seen, and the extravascular leakage of the contrast agent.