本文结合宫颈癌高剂量率后装内照射的临床实践,对内照射剂量率、剂量率效应机制、HDR及LDR内照射的放射生物学效应差异、HDR及LDR内照射放射生物剂量等方案的选择和等效方案换算以及HDR的适当分割次数等问题作了讨论,部分情况附以举例。并介绍了26个组6161例宫颈癌HDR内照射治疗的实施方案和并发症率的临床资料。 This article combined with the clinical practice of high dose rate postloading of cervical cancer, selection of internal radiation dose rate, dose rate effect mechanism, differences in radiobiological effects of HDR and LDR internal irradiation, HDR and LDR internal irradiation radiation biological dose, etc. The issues such as the conversion of equivalent schemes and the appropriate number of divisions of HDR were discussed, and examples were given in some cases. In addition, the clinical data of the implementation plan and complication rate of HDR internal radiation therapy for 2611 cases of cervical cancer in 26 groups were introduced.