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目的观察医务人员高尿酸血症(HUA)及影响因素logistic回归分析,为医务人员健康保健提供依据。方法 2012年健康体检医务人员2273人为调查对象,从20～88岁,按性别分5个年龄组检测血尿酸(BUA)水平,同时检测体质指数(BMI)、血常规、甲状腺功能、肾功能、血脂等。结果医疗卫生人员HUA发生率:男性12.97%,女性6.3%,男性高于女性(P<0.01),男性、空腹血糖(FPG)、甘油三酯(TG)、血肌酐(CR)、高密度脂蛋白胆固醇(HDL-C)、BMI与HUA显著性相关;HUA组与正常尿酸组异常率的比较:HUA组TG异常率(40.9%)、HDL-C低水平异常率(30.2%)、BMI(≥28)占22.0%、FPG异常率(10.7%),均高于正常尿酸组TG异常率(12.6%)、HDL-C低水平异常率(10.0%)、BMI(≥28)占9.6%、FPG异常率(5.7%);各组差异均有统计学意义(P<0.01)。结论医务人员HUA性别差异明显,男性更易发生高尿酸血症,且HUA者比尿酸正常人群更易发生超重、肥胖,因此提倡要合理饮食,积极锻炼,重视健康体检。
Objective To observe the hyperuricemia (HUA) of medical staffs and logistic regression analysis of influencing factors, and provide the basis for health care of medical staffs. Methods Totally 2273 medical staffs in 2012 were investigated. BUA was measured from 20 to 88 years old by sex in 5 age groups. BMI, blood routine, thyroid function, renal function, Lipids and so on. Results The prevalence of HUA among medical staff was 12.97% in male and 6.3% in female, higher in male than in female (P <0.01), male, fasting blood glucose (FPG), triglyceride (TG), serum creatinine The levels of HDL-C and BMI were significantly correlated with HUA. The abnormal rates of HUA group and normal uric acid group were higher than those of HUA group (40.9%), abnormal low HDL-C level (30.2%) and BMI ≥28) accounted for 22.0%, FPG abnormal rate (10.7%) were higher than normal uric acid group TG abnormal rate (12.6%), HDL-C low level abnormal rate (10.0%), BMI FPG abnormal rate (5.7%); The differences between the groups were statistically significant (P <0.01). Conclusion HUA gender differences in medical staff obvious, men are more prone to hyperuricemia, and HUA than the normal uric acid population is more prone to overweight and obesity, therefore advocating a reasonable diet, active exercise, emphasis on physical examination.