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目的研究介入治疗结合清宫术和药物治疗结合清宫术在剖宫产术后子宫瘢痕妊娠(CSP)患者治疗中的疗效。方法选取2013年2月至2016年4月间,于重庆市开州区人民医院确诊且接受治疗的剖宫产术后子宫瘢痕妊娠患者198例,按照治疗方法分为药物治疗组101例和介入治疗组97例。对比两组患者行清宫术时的出血量、血β-hHCG恢复正常情况、两组患者接受不同治疗到行清宫术之间的时间间隔、治疗结束后何时恢复正常月经、以及出现的副反应等。结果药物治疗组距清宫时间间隔为(7.72±2.94)d,高于介入治疗组的(2.25±0.34)d,差异有统计学意义(P<0.05);药物治疗组的出血量为(95.82±12.87)ml,高于介入治疗组的(39.48±5.97)ml,差异有统计学意义(P<0.05);介入治疗组患者的恢复正常月经时间及血β-hHCG恢复正常时间分别为(40.13±13.92)、(19.30±8.83)d,均短于药物治疗组的(59.87±9.98)和(29.71±3.86)d,差异有统计学意义;对比两组患者副反应的发生频率发现,差异无统计学意义。结论介入治疗结合清宫术相对于药物结合清宫术具有更大的优势,在临床上更适合治疗剖宫产术后子宫瘢痕妊娠。
Objective To investigate the efficacy of interventional therapy combined with curettage and drug therapy combined with curettage in the treatment of uterine scar pregnancy (CSP) after cesarean section. Methods A total of 198 patients with uterine scar pregnancy after cesarean section were diagnosed and treated in the People’s Hospital of Kaizhou City, Chongqing from February 2013 to April 2016. According to the treatment methods, 101 cases were divided into two groups: drug treatment group Treatment group of 97 cases. Comparing the two groups of patients undergoing curettage bleeding, blood β-hHCG return to normal, two groups of patients receiving different treatment to line the time interval between curettage, after the end of treatment when to resume normal menstruation, and the occurrence of side effects Wait. Results The time interval between two groups was 7.72 ± 2.94 days, which was significantly higher than that of the intervention group (2.25 ± 0.34) d (P <0.05). The bleeding volume of the drug-treated group was (95.82 ± 12.87) ml, higher than the intervention group (39.48 ± 5.97) ml, the difference was statistically significant (P <0.05); interventional treatment group patients with normal menstruation time and blood β-hHCG recovery time were (40.13 ± 13.92), (19.30 ± 8.83) d respectively, which were both shorter than those in the drug-treated group (59.87 ± 9.98) and (29.71 ± 3.86) d, with statistical significance; the frequency of side effects was not found in the two groups Significance of learning. Conclusion interventional therapy combined with curettage relative to the combination of medicine and curettage have greater advantages in the clinical treatment of uterine scar pregnancy after cesarean section.