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Pulmonaryalveolarproteinosis (PAP )wasfirstdescribedbyRosenetal1 in 195 8 PAPischaracterizedbytheaccumulationof proteinaceousmaterialinthealveolileadingtovaryingdegreesofimpairmentin gasexchange Recentstudiesdemonstratethatdeficiencyofgranulocyte macroph
Pulmonary alveolar proteinosis (PAP) was first described by Rosenetal 1 in 195 8 PAPischaracterizedby theaccumulationof proteinaceousmaterialinthealveolileadingtovaryingdegreesofimpairmentingasexchangeNewstudiesdemonstratethatdeficiencyofgranulocyte macroph