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目的探讨尼莫通对脑损伤后记忆障碍的疗效。方法124例患者随机分为尼莫通组(63例)和常规治疗组(61例),疗程均为一个半月。两组患者治疗前后均采用“临床记忆量表”进行检测,并行t检验。结果尼莫通组记忆商由75.2±17.9提高到92.1±14.2,对照组记忆商由75.9±18.7提高到86.1±16.6(P<0.05);且尼莫通组的指向记忆和图像自由回忆障碍改善尤为显著(P<0.001)。结论尼莫通对脑损伤后记忆障碍的疗效良好,且在复杂思维的恢复方面更为明显,主张伤后早期用药。
Objective To investigate the effect of nimotong on memory impairment after brain injury. Methods 124 patients were randomly divided into nimoton group (n = 63) and conventional treatment group (n = 61). The course of treatment was one and a half months. Two groups of patients before and after treatment were used “clinical memory scale” for testing, parallel t test. Results The nimodipine group’s memory quotient increased from 75.2 ± 17.9 to 92.1 ± 14.2, while that of the control group increased from 75.9 ± 18.7 to 86.1 ± 16.6 (P <0 .05); and the nimodipine group had a significant improvement in point memory and image free recall disorders (P <0.001). Conclusion Nimotong has a good effect on memory impairment after brain injury and is more obvious in the recovery of complex thinking, advocating the early post-injury medication.