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作者报告1例颈部放射治疗何杰金氏病后出现甲状腺机能紊乱的病例,男33岁。属ⅢA期。全淋巴节照射治疗28天,照射野包括颈、腋和纵隔。有20天日照射肿瘤剂量为35Gy。短期间隔后,对主动脉旁和腹股区又给相同剂量,病情完全缓解,13年后无复发。放疗后2年,患者体重增加,有便秘。临床上有粘液水肿表现。甲状腺功能确定甲状腺机能减退。采用甲状腺素治疗(0.1mg,3次/日),甲状腺机能迅速恢复正。前6年一切尚好,后出现甲亢症状,减量后,病情改善,身体状况良好达6个月,体重再次恢复,停用甲亢平,换用甲
The authors report a case of thyroid dysfunction following neck radiotherapy for Hodgkin’s disease, with a 33-year-old male. Is a IIIA period. The whole lymph node irradiation treatment for 28 days, the radiation field including the neck, hernia and mediastinum. There was a daily radiation dose of 35 Gy for 20 days. After the short-term interval, the same dose was given to the paraaortic and abdominal femoral areas, the condition was completely relieved, and there was no recurrence after 13 years. Two years after radiotherapy, the patient gained weight and had constipation. There is a clinical manifestation of myxedema. Thyroid function determines hypothyroidism. With thyroxine treatment (0.1mg, 3 times/day), thyroid function quickly returns to positive. In the first 6 years, everything was still good, after the onset of hyperthyroidism symptoms, after the reduction, the condition improved, physical condition was good for 6 months, weight recovered again, stop using hyperthyroidism, change armor