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目的研究糖尿病足溃疡的愈合,并对影响因素进行相关分析。方法回顾性研究2008年1月至11月我科住院治疗的106例糖尿病足溃疡患者愈合情况及其影响因素。结果患者年龄、贫血、溃疡深度、感染、骨髓炎、糖尿病外周神经病变、坏疽和血流灌注是影响愈合的危险因素(P均<0.05)。回归分析示骨髓炎、血流灌注、坏疽是影响愈合的独立危险因素。对不存在坏疽、骨髓炎和缺血的27例患者溃疡愈合情况研究发现,合并感染的溃疡愈合时间显著延长(P<0.05)。结论无论溃疡是否缺血,感染均是影响溃疡愈合的重要因素,及时就诊可以减少坏疽或骨髓炎的发生。
Objective To study the healing of diabetic foot ulcer and analyze the influencing factors. Methods A retrospective study of 106 cases of diabetic foot ulcer patients hospitalized in our department from January 2008 to November and the influencing factors were analyzed. Results Patient age, anemia, ulcer depth, infection, osteomyelitis, diabetic peripheral neuropathy, gangrene and perfusion were the risk factors for healing (all P <0.05). Regression analysis showed that osteomyelitis, perfusion and gangrene were independent risk factors for healing. The healing of ulcer in 27 patients without gangrene, osteomyelitis and ischemia found that the ulcer healing time was significantly prolonged (P <0.05). Conclusion Whether or not the ulcer is ischemia and infection are important factors that affect the healing of ulcer, timely treatment can reduce the incidence of gangrene or osteomyelitis.