目的　调查杭州市医务人员接触传染性非典型肺炎 (SARS)感染状况 ,探讨流行因素 ,评价防制措施。方法　对 2 0 0 3年杭州市密切接触SARS病例的 48名医务人员进行了流行病学调查和SARS抗体测定。结果　调查的 48名医务人员中 ,发病前接触 1名 ,发病后接触 48名 ;经常接触的有 3 5名 ( 72 9% ) ,偶尔接触 13名 ( 2 7 1% )。在隔离病房接触的有 48名 ,门诊接触 2名 ;以诊治病人接触为主 (占 80 % ) ,其次是给病人打针和护理病人等 ;有 70 8%的人接触病人的血液和分泌物 ,有 5 2 1%的人接触病人的排泄物 ;与SARS病人在 1米以内接触的有 47名 (占 97 9% ) ,在 1～ 2米接触的 1名 (占 2 1% )。 48名医务人员接触SARS病人时 ,防护措施严密 ,双份血清测定SARS抗体IgG均阴性。结论　杭州市密切接触SARS病例的医务人员未发现感染 ,采取严密防护是预防SARS感染的关键措施 Objective To investigate the status of medical workers exposed to SARS in Hangzhou, discuss the epidemic factors and evaluate the control measures. Methods An epidemiological survey and SARS antibody test were performed on 48 medical workers in Hangzhou who were in close contact with SARS cases in 2003. Results Among the 48 medical staff surveyed, there were 1 pre-illness contact and 48 post-illness onset; 35 (72.9%) were regularly exposed and 13 (271%) were occasionally exposed. 48 were in isolated ward contacts and 2 were in outpatient clinics; the majority were contact diagnosis and treatment (80%), followed by injections and nursing of patients; 70.8% of the patients were exposed to the patient’s blood and secretions, Fifty-two (1)% of the population contacted the patient’s excrement, 47 (97.9%) contacted the SARS patient within 1 meter, and 1 (1-2.1%) contacted between 1-2 meters. When 48 medical staff contacted SARS patients, the protective measures were rigorous, and the serum IgG of SARS was negative by double serum assay. Conclusions No serious infection was found in medical staff in Hangzhou who were in close contact with SARS cases, and strict protection was the key measure to prevent SARS infection