化脓性脑膜炎(简称化脑)是一种小儿时期、尤其是婴幼儿较多见而严重的疾病。近年来,笔者常亲自和建议采取鞘内注射抗菌素作为化脑的一项治疗。现举出四例(前三例来自附属医院,第四例是泰安地区医院的)报告于下;并复习文献,探讨化脑的病原菌、抗菌素疗法等。希对读者有所裨益。 Purulent meningitis (referred to as the brain) is a childhood, especially infants and young children more common and serious disease. In recent years, I often personally and recommended to take intrathecal antibiotics as a treatment of the brain. Four cases (the first three are from affiliated hospitals and the fourth is Tai’an Regional Hospital) are listed below; and the literature is reviewed to explore the pathogenic bacteria and antimicrobial therapy of the brain. Hope for the benefit of readers.