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肝动脉插管栓塞化疗（ＴＡＣＥ）是目前临床上非手术治疗原发性肝癌（ＰＬＣ）的主要手段之一。但这种方法常引起上消化道粘膜的损伤，导致上消化道出血等［１］，影响化疗的继续及疗效。Ｌｏｓｅｃ具强力抑酸作用，可以预防多种应激状态下消化道的损伤，减少上消化道出血的发
Transcatheter arterial chemoembolization (TACE) is currently one of the main methods for non-surgical treatment of primary liver cancer (PLC). However, this method often causes damage to the upper gastrointestinal mucosa, leading to upper gastrointestinal bleeding, etc. [1], affecting the continued chemotherapy and efficacy. Losec has a strong acid-suppressing effect to prevent damage to the digestive tract in a variety of stress states and reduce the risk of upper gastrointestinal bleeding.