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细胞膜上Toll样受体和胞浆内核苷酸结合寡聚结构域样受体是两类主要的先天免疫模式识别受体,它们通过诱发非感染性炎症反应并相互协同参与动脉粥样硬化的发生和发展,是介导先天免疫反应与动脉粥样硬化发生的桥梁。
Toll-like receptors and cytoplasmic nucleotide-binding oligomeric domain-like receptors on the plasma membrane are two major classes of innate immune pattern recognition receptors that induce atherosclerosis by inducing a noninfectious inflammatory response and interacting synergistically with each other And development, is mediated by the innate immune response and atherosclerosis bridge.