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细胞焦亡作为一种新的促炎程序性细胞死亡方式被逐渐研究阐述，其形态学特征、发生机制、作用机制与其他细胞死亡方式（如凋亡、坏死等）有显著不同。细胞焦亡不仅与感染性疾病密切相关，而且与动脉粥样硬化性疾病、代谢性疾病、重要脏器非细菌性炎性疾病等的发生、发展密切相关。通过对细胞焦亡作用机制及相关疾病的深入研究，有助于深入了解相关疾病的发生和发展，为临床疾病的防治提供新方向。“,”As a new form of pro-inflammatory programmed cell death,pyroptosis is gradually studied and described.The mechanism,morphological and biochemical properties of pyroptosis are significantly different from other cell deaths such as apoptosis and necrosis.Pyroptosis is not only closely related to infectious disea-ses,but also plays a significant role in atherosclerosis, metabolic diseases and vital organs non-bacterial inflammatory disease.The in-depth research of its mechanisms in related diseases contributes to the under-standing of the occurrence and development of cell death-related diseases,which may provide a new direction for the prevention and treatment.