论文部分内容阅读
目的 确定反流性食管炎内镜观察结果与胃食管反流严重程度之间的相关性。方法 有典型胃食管反流症状者54例,全部接受内镜检查,其中无食管炎29 例,无并发症的食管炎25 例;通过对内镜下粘膜表现、食管测压、24 小时食管pH 监测的观察结果进行相关分析。结果 食管粘膜内镜下白色渗出物的出现、损害的范围与胃食管反流的严重程度有显著的相关性,无白色渗出物的红色损害也与病理性胃食管反流相关。下食管括约肌静息压、下食管括约肌一过性松弛率、食管中下段蠕动波传导速度、异常收缩发生率均有显著异常(P< 0.01)。pH< 4的总时间% 在有粘膜红色损害、白色损害和融合损害的患者中分别为6.4% 、9.9% 、34.0% (P< 0.01)。结论 内镜所见食管粘膜红色损害与病理性胃食管反流明显相关,白色损害与较严重的反流相关,损害范围与反流平均时间相关。在反流性食管炎诊断的分类中,除损害区出现白色渗出物和损害的范围是重要的观察指标外,红色损害也值得观察
Objective To determine the correlation between the endoscopic findings of reflux esophagitis and the severity of gastroesophageal reflux disease. Methods A total of 54 patients with typical symptoms of gastroesophageal reflux were enrolled in this study. All patients underwent endoscopy, including 29 without esophagitis and 25 without esophagitis. The endoscopic mucosal findings, esophageal manometry, 24-hour esophageal pH Monitoring the results of the correlation analysis. Results The occurrence of white exudate in endoscopic esophageal mucosa showed a significant correlation with the severity of gastroesophageal reflux. The red lesions without white exudate were also associated with pathological gastroesophageal reflux. The resting pressure of the lower esophageal sphincter, the transient relaxation rate of the lower esophageal sphincter, the peristaltic wave velocity in the middle and lower esophagus and abnormal contraction were significantly different (P <0.01). The total time% of pH <4 was 6.4%, 9.9%, 34.0%, respectively (P <0.01) in patients with mucosal red lesions, white lesions and fusion lesions. Conclusions The red lesions of esophageal mucosa detected by endoscopy are significantly correlated with pathological gastroesophageal reflux. The white lesions are associated with more severe reflux, and the extent of damage is related to the average time of reflux. In the classification of reflux esophagitis diagnosis, except for the area of white exudate damage and damage is an important indicator of the scope of the observation, the red damage is also worth observing