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对54例急性单纯酒精中毒患者随机分组，比较盐酸纳洛酮（NX）舌下含片与常规治疗的疗效。结果表明，NX舌下含片可使酒精中毒者症状迅速缓解，明显缩短中毒后各项恢复时间，其疗效时间与文献报告的NX静脉给药相近。对轻度中毒者比较不同首剂量发现，首剂量0．8mg较0．4mg疗效更为明显。本文结果显示，NX舌下含片治疗急性酒精中毒疗效确实，而较静脉给药更为简便、安全、经济。
Fifty-four patients with acute alcoholism were randomly divided into two groups. The sublingual tablets of naloxone hydrochloride were compared with those of routine treatment. The results showed that NX sublingual tablets can quickly relieve the symptoms of alcoholism, significantly shorten the recovery time after poisoning, the curative effect of time and reported in the literature similar to the NX intravenous administration. Mild poisoning compared with the first dose found that the first dose of 0.8mg more effective than 0.4mg more obvious. The results of this study show that the sublingual tablet of NX for the treatment of acute alcoholism is indeed effective, and more convenient than intravenous administration, safe and economical.