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目的分析某企业集团纳米二氧化钛(钛白粉)生产作业工人的健康状况探讨钛白粉及其生产装置存在或产生的职业病危害因素对劳动者健康的影响。方法选择某企业集团从事钛白粉生产作业的工人199名作为暴露组,选取某能源公司116名管理工作人员作为对照组,通过对研究对象基本情况调查、钛白粉生产作业现场职业病危害因素调查、职业健康检查及普通健康检查等收集相关资料应用Excel 2003和SPSS 19.0软件包对数据进行录入和统计学分析。结果暴露组肺功能1秒用力呼气容积、用力肺活量(FEV_1、FVC)和FEV_1/FVC)低于对照组(P<0.05);肝功能中白蛋白、球蛋白、白球比与对照组比较,差异有统计学意义(P<0.05);两组尿常规检验结果显示,对照组尿比重均值略高于暴露组,而暴露组尿pH均值则高于对照组,差异均有统计学意义(P<0.05);血液分析情况比较:暴露组有115人存在1项以上血液指标异常,对照组为52人,分别占57.8%和44.8%,总体异常率及红细胞分布宽度变异系数、红细胞分布宽度、红细胞平均体积、平均血红蛋白浓度、红细胞压积、血小板分布宽度、平均血小板体积均值与对照组比较也有所差异(P<0.05)。结论钛白粉及其生产装置存在或产生的职业病危害因素对劳动者健康的影响是多方面的,钛白粉生产企业应有针对性地加强重点岗位职业病危害因素的治理和作业人员的个体防护。
Objective To analyze the health status of workers in a group of enterprises with nano titanium dioxide (titanium dioxide) production and to explore the impact of occupational hazards on the health of workers in the presence or production of titanium dioxide and its production equipment. Methods A total of 199 workers engaged in the production of titanium dioxide in an enterprise group were selected as the exposure group. 116 management staff members of a certain energy company were selected as the control group. Based on the investigation of the basic conditions of the study subjects, the occupational hazards in the titanium dioxide production site investigation, Health checkup and general health check-up and other relevant information collected using Excel 2003 and SPSS 19.0 software package for data entry and statistical analysis. Results The forced expiratory volume, forced vital capacity (FEV 1, FVC) and FEV 1 / FVC of lung function in the exposed group were lower than those in the control group (P <0.05). Compared with the control group, (P <0.05). The results of urine routine test showed that the average urine specific gravity of the control group was slightly higher than that of the exposed group, but the urinary pH of the exposed group was higher than that of the control group (P <0.05). Comparison of blood analysis: there were 115 blood test abnormalities in the exposed group (52 patients in the control group), accounting for 57.8% and 44.8% respectively. The overall abnormality rate, the coefficient of variation of the width of erythrocyte distribution, the distribution width of erythrocytes, The average volume of red blood cells, mean hemoglobin concentration, hematocrit, platelet distribution width and mean platelet volume were also significantly different from the control group (P <0.05). Conclusion There are many influences on the health of laborers caused by occupational hazards that exist or are caused by titanium dioxide powder and its production equipment. Titanium dioxide producers should strengthen the management of occupational hazards in key positions and the individual protection of workers in a targeted manner.