论文部分内容阅读
以邻香兰醛和甘氨酸、Ｌ甲硫氨酸在氢氧化钾的乙醇溶液中合成Ｓｃｈｉｆ碱配体Ｌ１Ｋ，Ｌ２Ｋ（Ｌ１＝Ｃ１０Ｈ１０Ｏ４ＮＫ·Ｈ２Ｏ，Ｌ２＝Ｃ１３Ｈ１６ＮＯ４ＳＫ），将其分别作用于稀土Ｌｎ３＋，配位后生成１１个新配合物：Ｌｎ（Ｌ１）３·ｎＨ２Ｏ（Ｌｎ＝Ｌａ，ｎ＝０；Ｌｎ＝Ｐｒ，Ｎｄ，ｎ＝１；Ｌｎ＝Ｓｍ，Ｅｕ，Ｄｙ，ｎ＝２），Ｌｎ（Ｌ２）３·ｎＨ２Ｏ（Ｌｎ＝Ｌａ，ｎ＝１；Ｌｎ＝Ｐｒ，Ｓｍ，Ｅｕ，Ｄｙ，ｎ＝２），对其进行红外光谱、紫外光谱、摩尔电导、氢核磁共振谱及元素分析，推测Ｓｃｈｉｆ碱配体是以Ｏ—Ｎ—Ｏ的三齿形式与中心金属离子配位的，中心金属离子的配位数为９～１１．同时对两类配合物中的９个新化合物进行了抗肿瘤活性的初步筛选
The Schiff base ligands L1K, L2K (L1 = C10H10O4NK · H2O, L2 = C13H16NO4SK) were synthesized from o-vanillin, glycine and L-methionine in ethanolic solution of potassium hydroxide, Eleven new complexes were formed after coordination: Ln (L1) 3 · nH2O (Ln = La, n = 0; Ln = Pr, Nd, n = 1; Ln = Sm, Eu, Dy, n = 2) (L2) 3 · nH2O (Ln = La, n = 1; Ln = Pr, Sm, Eu, Dy and n = 2) were synthesized and characterized by FTIR, UV- It is speculated that the Schif base ligand is coordinated with the central metal ion in the tridentate form of O-N-O, and the coordinate number of the central metal ion is 9-11. At the same time, nine new compounds from two kinds of complexes were initially screened for antitumor activity