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用补阳还五汤治疗气虚血瘀型慢性原发性肾小球肾炎３１例，观察治疗前后血浆内皮素（ＥＴ）、降钙素基因相关肽（ＣＧＲＰ）水平，及临床疗效，并与健康组对照。结果：治疗前ＥＴ显著高于健康组（Ｐ＜０．０１），ＣＧＲＰ显著低于健康组（Ｐ＜０．０１），治疗后均显著改善（Ｐ＜０．０１），临床症状也明显改善，疗效显著（总有效率为８３．９％）。表明补阳还五汤对气虚血瘀型慢性肾炎ＥＴ、ＣＧＲＰ有调节作用
Treating 31 cases of chronic primary glomerulonephritis with qi deficiency and blood stasis with Buyang Huanwu Decoction, observe the levels of plasma endothelin (ET) and calcitonin gene-related peptide (CGRP) before and after treatment, and observe the clinical curative effect and health Group control. Results: Before treatment, ET was significantly higher than that of healthy group (P<0.01), CGRP was significantly lower than that of healthy group (P<0.01), and it was significantly improved after treatment (P<0.01). Clinical symptoms also improved significantly. The effect is significant (the total effective rate is 83.9%). Demonstrate that Buyang Huanwu Decoction regulates ET and CGRP in chronic nephritis with qi deficiency and blood stasis type