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用补阳还五汤治疗气虚血瘀型慢性原发性肾小球肾炎31例,观察治疗前后血浆内皮素(ET)、降钙素基因相关肽(CGRP)水平,及临床疗效,并与健康组对照。结果:治疗前ET显著高于健康组(P<0.01),CGRP显著低于健康组(P<0.01),治疗后均显著改善(P<0.01),临床症状也明显改善,疗效显著(总有效率为83.9%)。表明补阳还五汤对气虚血瘀型慢性肾炎ET、CGRP有调节作用
Treating 31 cases of chronic primary glomerulonephritis with qi deficiency and blood stasis with Buyang Huanwu Decoction, observe the levels of plasma endothelin (ET) and calcitonin gene-related peptide (CGRP) before and after treatment, and observe the clinical curative effect and health Group control. Results: Before treatment, ET was significantly higher than that of healthy group (P<0.01), CGRP was significantly lower than that of healthy group (P<0.01), and it was significantly improved after treatment (P<0.01). Clinical symptoms also improved significantly. The effect is significant (the total effective rate is 83.9%). Demonstrate that Buyang Huanwu Decoction regulates ET and CGRP in chronic nephritis with qi deficiency and blood stasis type