论文部分内容阅读
急性重度亚硝酸盐中毒是内科急症,可出现口唇甲床、全身皮肤青紫,血压下降,意识障碍,呼吸衰竭等危及生命情况,须尽快有效救治。1992～1999年间我院急诊科共救治了急性重度亚硝酸盐中毒患者28例,其中12例使用纳络酮,取得满意效果。1 资料和方法1.1 临床资料 1992～1999年收治的重度亚硝酸盐中毒28例患者,均为男性,体健无疾病史。均经查静脉血高铁血红蛋白血呈阳性证实。其中1992～1995年16例,年龄 21～44岁,治疗药物以亚甲蓝为主,为对照组;1996年～1999年12例,年龄19～42岁,治疗药物亚甲蓝+纳络酮为主,为治疗组。均误食亚硝酸盐后15分种内出现症状。均发生口唇甲床全身皮肤青紫、胸闷憋气、肢体麻木、冷汗、血压下降、呼吸困难。两组中均有4例出现不同程度的意识障碍。治疗组中有1例伴有呼吸浅弱不规则。两组患者血气分析结果均显示低氧血症和轻度呼吸性酸中毒。
Acute severe nitrite poisoning is a medical emergency, there may be lip and nail bed, systemic skin bruising, decreased blood pressure, disturbance of consciousness, respiratory failure and other life-threatening conditions, effective treatment as soon as possible. From 1992 to 1999, 28 cases of acute severe nitrite poisoning were treated in emergency department of our hospital. Among them, naloxone was used in 12 cases and satisfactory results were obtained. 1 Materials and Methods 1.1 Clinical data 1992 to 1999 admitted to the severe nitrite poisoning 28 patients, all men, no history of physical health. All were confirmed by venous blood methemoglobin hemoglobin test. Among them, from 1992 to 1995, 16 cases were aged from 21 to 44 years old. The treatment drugs mainly consisted of methylene blue, which was the control group. From 1996 to 1999, 12 cases were aged from 19 to 42 years. The therapeutic drugs methylene blue and naloxone Mainly for the treatment group. Symptoms were observed within 15 minutes after eating nitrite. Have occurred on the lips bed body bruising, chest tightness, suffocation, numbness, cold sweat, blood pressure, breathing difficulties. In both groups, 4 patients showed different degrees of disturbance of consciousness. One patient in the treatment group had irregular shallow breathing. Blood gas analysis results of both groups showed hypoxemia and mild respiratory acidosis.