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本文采用辣根过氧化物酶（ＨＲＰ）组化方法，对大鼠延髓腹外侧表面化学感受区与延髓内部核团之间的神经结构联系进行了系统的探查。实验在３０只麻醉且自主呼吸的雄性ＳＤ大鼠上分四组进行。用ＨＲＰ滤纸分别局部敷贴于延髓腹外侧表面的头端化学感受区（Ｒ区，ｎ＝１０）、尾端化学感受区（Ｃ区，ｎ＝１０）、中间区（Ⅰ区，ｎ＝６）和对照区（ｎ＝４）。动物存活２４ｈ后，检查ＨＲＰ标记细胞所在的核团部位。（１）于Ｒ区表面敷贴ＨＲＰ后，在延髓斜方体核（Ｔｚ）、外周橄榄腹外侧核（ＬＶＰＯ）和斜方体后核（ＮＲＴ）均有ＨＲＰ标记细胞存在。（２）于Ｃ区表面敷贴ＨＲＰ后，在延髓的巨细胞旁外侧核（ＬＰＧｉ）、外侧网状核（ＬＲｔ）和舌下神经核有ＨＲＰ标记细胞存在。（３）于Ⅰ区表面敷贴ＨＲＰ后，在６只大鼠的延髓内部区域仅观察到８个ＨＲＰ标记细胞，它们散在地分布于巨细胞旁外侧核的腹侧部分。（４）于对照区敷贴ＨＲＰ后，在４只大鼠的延髓内部区域仅观察到６个ＨＲＰ标记细胞，它们散在地分布在头端腹外侧网状核（ＲＶＬ）。上述结果提示：Ｔｚ，ＬＶＰＯ，ＮＲＴ，ＬＰＧｉ和ＬＲｔ等延髓内部核团与腹外侧表面化学感受区之间存在神经结构联系，这可能为延髓腹侧面起化学感受器作用?
In this study, HRP histochemistry was used to systematically investigate the neural connections between the rostral ventrolateral medulla and the medulla oblongata. The experiment was performed in four groups on 30 anesthetized and spontaneously resuscitated male SD rats. The top of the rostral chemosensory zone (R zone, n = 10), the caudal chemical sensing zone (zone C, n = 10) and the middle zone (zone Ⅰ, n = 6 ) And control area (n = 4). After the animals survived for 24 h, the nuclei sites where the HRP-labeled cells were located were examined. (1) HRP-labeled cells were present in the R zone after application of HRP on both Tz, LVPO and NRT. (2) HRP-labeled cells existed in the medulla oblongata medulla oblongata (LPGi), lateral reticular nucleus (LRt) and hypoglossal nucleus after application of HRP on the surface of C area. (3) After HRP was applied to the surface of area Ⅰ, only 8 HRP-labeled cells were observed in the medulla oblongata of 6 rats, which scatteredly distributed in the ventral part of the lateral ventricle of the giant cell. (4) After application of HRP in the control area, only 6 HRP-labeled cells were observed in the medulla oblongata of 4 rats interspersed with RVL. The above results suggest that there is a neuro-structural relationship between the medulla oblongata inner nucleus such as Tz, LVPO, NRT, LPGi and LRt, and the surface of the ventrolateral medulla, which may play a role of chemoreceptor in the ventral medulla oblongata.