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目的 :了解本院抗精神病药的应用状况及发展趋势。方法 :采用金额排序和频度分析方法对本院 1999～ 2 0 0 2年抗精神病药的应用情况进行统计分析。结果 :抗精神病药的年用药金额及治疗日数 (DDDs)逐年提高 ,2 0 0 2年各种抗精神病药年用药金额及DDDs分别是 1999年的 2 .15倍和 1.37倍。氯氮平、氯丙嗪、舒必利、奋乃静的DDDs始终分别列在前四位。非典型抗精神病药年用金额及DDDs增长幅度较大 ,其中氯氮平、利培酮临床使用率较高 ,其DDDs始终列第一和第五位 ,所占金额比例也较大。结论 :非典型抗精神病药的使用有逐年上升的趋势 ,应用前景广阔 ;尚需开发出疗效确切、价格低廉、毒副作用小的抗精神病药。
Objective: To understand the application status and development trend of antipsychotics in our hospital. Methods: Using the amount of ranking and frequency analysis of the hospital from 1999 to 2002 antipsychotic application of statistical analysis. Results: The annual amount of antipsychotic medication and the number of treatment days (DDDs) increased year by year. The amount of annual antidiabetic medication and DDDs in 2002 were 2.15 times and 1.37 times respectively. Clozapine, chlorpromazine, sulpiride, and perphenazine DDDs are always listed in the top four. The annual amount of atypical antipsychotic drugs and DDDs increased greatly. Among them, clozapine and risperidone had a high clinical utilization rate. DDDs ranked the first and fifth place with a larger proportion. Conclusion: The use of atypical antipsychotics has been increasing year by year with broad application prospect. Antipsychotics with definite effect, low price and little toxic side effect need to be developed.