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为了解正常小儿对人巨细胞病毒(HCMV)的感染状况,用ELISA法、选择两种不同厂家的试剂、对218名儿童血抗HCMV-IgM和抗HCWV-IgG进行了检测,以共同阳性作为结果判断依据,、结果218名儿童血抗HCMV-IgM阳性率为30.2%、抗HCMi-IgG阳性率为73.8%,血抗HCMV抗体与性别之间没有明显差异,但一岁以内小儿抗 HCMV-IgM阳性率为 11.5%, 较一岁以后低,有显著意义。血抗 HCMV-IgM阳性率随着年龄的增长而增高,一岁以内、一至五岁与五岁以后年龄组差异非常显著。小儿血抗HCMV抗体的检出率与小儿年龄、小儿的免疫应答能力和传播途径有关。较高的检出率说明了小儿HCMV携带者的比例较高及人对HCMV普遍易感,应加强预防措施,防止HCMV在人群中的传播。
In order to understand the status of human cytomegalovirus (HCMV) infection in normal children, 218 children with anti-HCMV-IgM and anti-HCWV-IgG were detected by ELISA using two kinds of reagents from different manufacturers. The results are based on the judgment, the results of 218 children blood anti-HCMV-IgM positive rate was 30.2%, anti-HCMi-IgG positive rate was 73.8%, blood anti-HCMV antibody and gender did not differ significantly, but within one year The positive rate of anti-HCMV-IgM in children was 11.5%, which was lower than that of the first year old, which had significant significance. The positive rate of blood anti-HCMV-IgM increased with age. Within one year of age, the difference between the age group of one to five and the age of five was very significant. The detection rate of pediatric blood anti-HCMV antibody is related to pediatric age, pediatric immune response ability and transmission route. The higher detection rate indicates a higher proportion of children with HCMV carriers and general susceptibility to HCMV. Precautionary measures should be strengthened to prevent the spread of HCMV in the population.