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选取我院2014年7月-2015年1月收治的老年糖尿病患者86例,分为对照组和观察组各43例,对照组给予患者常规的胰岛素治疗,治疗过程中按监测的血糖值调整胰岛素用量。观察组在对照组基础上联用格列美脲,初始剂量1mg,之后服用剂量2~4mg,每日一次,早餐前服用。三个月后。结果两组患者HbA_(1C)值、PBG值、FPG值均较治疗前降低,且观察组值显著低于对照组(P<0.05);观察组有效率为95.35%,对照组79.06%(P<0.05);观察组胰岛素用量为(30.8±2.7)U/d,对照组为(39.9±2.1)U/d,(P<0.05)。结论采用格列美脲联合胰岛素法。
A total of 86 elderly patients with diabetes mellitus were enrolled in our hospital from July 2014 to January 2015, and divided into control group and observation group, with 43 cases in each group. Patients in the control group were given routine insulin therapy. During the treatment, insulin was adjusted according to the monitored blood glucose level Amount. The observation group was treated with glimepiride on the basis of the control group, the initial dose of 1mg, after taking the dose of 2 ~ 4mg, once daily, before taking breakfast. Three months later. Results The HbA 1 C, PBG and FPG in both groups were significantly lower than those before treatment (P <0.05). The effective rate was 95.35% in the observation group and 79.06% in the control group (P <0.05). The amount of insulin in the observation group was (30.8 ± 2.7) U / d and that in the control group was (39.9 ± 2.1) U / d, (P <0.05). Conclusion The use of glimepiride combined with insulin method.