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目的 探讨心肌肌钙蛋白I(CTnI)诊断急性心肌梗塞 (AMI)的价值。方法 采用固相层析免疫技术定性检测三组分别确诊为AMI、不稳定性心绞痛 (UA)、陈旧性心肌梗塞 (OMI)病人血清中的CTnI ,同时检测病人血清肌酸激酶同工酶 (CK -MB)。结果 3 0例AMI病人CTnI均为阳性 ;3 0例UA病人 3例阳性 ;3 0例OMI病人均为阴性。对应的CK -MB增高分别为 2 0例、9例和 4例。CTnI诊断AMI的敏感性为 10 0 % ,CK -MB为 66.7% ,χ2 =8.1,P <0 .0 1。结论 CTnI对诊断AMI有很高的特异性和敏感性
Objective To investigate the value of cardiac troponin I (CTnI) in the diagnosis of acute myocardial infarction (AMI). Methods The serum levels of CTnI in three groups diagnosed as AMI, unstable angina pectoris (UA) and old myocardial infarction (OMI) were detected by solid phase chromatography immunoassay. The levels of serum creatine kinase (CK) -MB). Results CTnI was positive in 30 cases of AMI patients, 3 cases of 30 cases of UA patients and 30 cases of OMI patients were negative. Corresponding CK-MB increased were 20 cases, 9 cases and 4 cases. The sensitivity of CTnI in the diagnosis of AMI was 100%, CK-MB was 66.7%, χ2 = 8.1, P <0.01. Conclusion CTnI has high specificity and sensitivity in the diagnosis of AMI