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目的探讨消化性溃疡应用左氧氟沙星、阿莫西林四联疗法根除幽门螺杆菌(Hp)的疗效。方法消化性溃疡的患者96例,分为A组(克拉霉素+甲硝唑+泮托拉唑+枸橼酸铋钾治疗)、B组(克拉霉素+阿莫西林+泮托拉唑+枸橼酸铋钾治疗)、C组(左氧氟沙星+阿莫西林+泮托拉唑+枸橼酸铋钾治疗),各32例。观察Hp的根除率。结果 C组Hp根除率高于A、B组,差异有统计学意义(P<0.05)。结论左氧氟沙星联合阿莫西林的四联疗法Hp根除率高,无明显不良反应,值得临床推广。
Objective To investigate the efficacy of levofloxacin and amoxicillin quadruple therapy for the eradication of Helicobacter pylori (Hp) in patients with peptic ulcer. Methods A total of 96 patients with peptic ulcer were divided into group A (clarithromycin + metronidazole + pantoprazole + bismuth potassium citrate), group B (clarithromycin + amoxicillin + pantoprazole + Bismuth potassium citrate treatment), C group (levofloxacin + amoxicillin + pantoprazole + bismuth potassium citrate treatment), each 32 cases. Hp eradication rate observed. Results The eradication rate of Hp in group C was higher than that in group A and B, the difference was statistically significant (P <0.05). Conclusion Levofloxacin combined with amoxicillin quadruple therapy Hp eradication rate, no obvious adverse reactions, worthy of clinical promotion.