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目的:研究常见的发病危险因素,为新生儿医院感染的诊疗提供科学依据。方法:首先查阅96例医院感染新生儿的病例资料,采用病例对照研究的方法,以此96例患儿为病例组,另从同期住院但未曾发生医院感染的新生儿中随机抽取128例作为对照组,通过单因素分析揭示导致新生儿医院感染的危险因素。结果:医院感染相关因素:气管插管、PICC、胃肠外营养、机械通气、CPAP、留置胃管、预防性应用抗生素、早产、低出生体重、基础疾病均为医院感染发生的高危因素。结论:器械侵入、早产、低出生体重、基础疾病等是本病的危险因素,明确感染的危险因素是控制和预防院内感染的必要条件。
Objective: To study the common risk factors of morbidity and provide a scientific basis for the diagnosis and treatment of neonatal nosocomial infections. Methods: First of all 96 cases of hospital-acquired neonatal cases were examined. A case-control study was conducted. Ninety-six children were selected as case group, and 128 newborns were randomly selected from neonates hospitalized for the same period but without nosocomial infection. Group, univariate analysis revealed the risk factors leading to neonatal nosocomial infections. Results: Nosocomial infection related factors: tracheal intubation, PICC, parenteral nutrition, mechanical ventilation, CPAP, indwelling gastric tube, prophylactic antibiotics, premature birth, low birth weight and underlying diseases are all risk factors for nosocomial infections. CONCLUSION: Instrument invasion, premature birth, low birth weight and underlying diseases are the risk factors of this disease. Identifying the risk factors of infection is a necessary condition for the control and prevention of nosocomial infections.