论文部分内容阅读
目的分析研究放射性免疫分析法测定血清癌胚抗原在肺部良恶性疾病中的临床应用。方法选取2010年1月至2012年1月在我院诊断明确的肺癌与肺结核患者,分肺癌组64例,肺结核组(对照组)68例。采用放射性免疫分析法检测所有患者的血清癌胚抗原水平。结果肺癌患者相对于结核组患者CEA阳性率较高为31.2%,有百分百的特异度和阳性预测值,且随着肺癌病程的延长,CEA的浓度值亦明显递增,差异有统计学意义(P<0.05)。结论放射性免疫分析法测定CEA水平对于肺癌的诊断有较高的价值,对于判断病情进展、肿瘤预后等都有较重要的意义。
Objective To study the clinical application of radioimmunoassay in the detection of serum carcinoembryonic antigen in benign and malignant pulmonary diseases. Methods From January 2010 to January 2012, 64 patients with lung cancer and pulmonary tuberculosis diagnosed in our hospital were classified into lung cancer group and 68 pulmonary tuberculosis group (control group). Radioimmunoassay was used to detect serum CEA levels in all patients. Results The positive rate of CEA in patients with lung cancer was significantly higher than that of patients with tuberculosis (31.2%), with 100% specificity and positive predictive value. With the prolongation of lung cancer, the concentration of CEA was also significantly increased, the difference was statistically significant (P <0.05). Conclusion Radioimmunoassay for the determination of CEA levels for the diagnosis of lung cancer have a higher value, for the judgment of disease progression, tumor prognosis, etc. are more important.