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通过对２４７８例等待肾脏移植受者的ＨＬＡ体液致敏状态的观察，进行移植受者群体反应性抗体（ＰＲＡ）的研究及其与肾脏移植的关联。结果显示，ＰＲＡ是移植前受者是否致敏的指标，与淋巴细胞毒（ＣＤＣ）的不相合呈正相关，ＰＲＡ≥３０．００％的受者接受ＣＤＣ阴性移植肾仍然全部发生超急排斥，而ＰＲＡ阴性受者仅为１２．４６％。因此，ＰＲＡ分析对辨别ＨＬＡ基因的免疫状态和预测超急排斥反应以及改善肾脏移植的效果具有普遍意义。
Through the observation of 2478 HLA allergen status in kidney transplant recipients, the study of PRA and its correlation with renal transplantation were performed. The results showed that PRA was an indicator of sensitization before transplantation and was positively correlated with the mismatch of lymphocyte cytotoxicity (CDC). All patients with PRA ≥30.00% underwent CDK negative allograft rejection. PRA negative recipients only 12.46%. Therefore, PRA analysis is of general significance for identifying the immune status of HLA genes and predicting the effects of hyperacute rejection and improving kidney transplantation.