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目的对比分析阿托伐他汀、辛伐他汀、瑞舒伐他汀对高脂血症的治疗效果。方法选择2014年1月—2016年1月在商南县医院进行诊治的高脂血症患者120例,随机分为阿托伐他汀组、辛伐他汀组以及瑞舒伐他汀组,分别采用阿托伐他汀、辛伐他汀、瑞舒伐他汀治疗,3组均治疗8周。比较3组治疗前、治疗第4周和治疗第8周的血脂水平,以及不良反应发生情况。结果 3组治疗第4周和治疗第8周的血脂水平均明显改善,同组治疗前后比较差异有统计学意义(P<0.05);且瑞舒伐他汀组明显优于阿托伐他汀组和辛伐他汀组,组间比较差异有统计学意义(P<0.05)。3组的不良反应发生率相比无明显差异。结论阿托伐他汀、辛伐他汀和瑞舒伐他汀均可以有效改善高脂血症患者的血脂水平,且瑞舒伐他汀的治疗效果最佳。
Objective To compare and analyze the therapeutic effect of atorvastatin, simvastatin and rosuvastatin on hyperlipidemia. Methods 120 patients with hyperlipidemia who were diagnosed and treated in Shangnan County Hospital from January 2014 to January 2016 were randomly divided into atorvastatin group, simvastatin group and rosuvastatin group. Atorvastatin, simvastatin, rosuvastatin treatment, three groups were treated for 8 weeks. The levels of blood lipids in the three groups before treatment, the fourth week of treatment and the eighth week of treatment were compared, and the occurrence of adverse reactions were compared. Results The levels of blood lipid in the third week and the eighth week of treatment were significantly improved in the three groups (P <0.05), and the rosuvastatin group was significantly better than the atorvastatin group Simvastatin group, there was significant difference between the two groups (P <0.05). There was no significant difference in the incidence of adverse reactions between the three groups. Conclusion Both atorvastatin, simvastatin and rosuvastatin can effectively improve the level of blood lipids in patients with hyperlipidemia, and rosuvastatin has the best therapeutic effect.