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近10年中,确立了乳腺癌的保守手术治疗、辅助性细胞抑制剂和内分泌治疗及乳腺癌的全身影像检查。虽然保守手术是可行的,但对治疗范围或病人选择何种治疗方式适宜仍有不同意见。另外,在系统辅助治疗中,其作用机理及对患者是否有益等最基本的问题仍有争论。局部复发的决定因素1.肿瘤相关因素:研究发现二种与局部复发相关的因素,即原发肿瘤组织体积与组织学类型。EORTC试验组和阿姆斯特丹的资料提示,在乳腺癌保守治疗指征范围内,原发肿瘤体积无影响。Ⅰ、Ⅱ期肿瘤的局部复发率相
In the last 10 years, conservative surgery for breast cancer, helper cytostatics and endocrine therapy, and full-body imaging of breast cancer have been established. Although conservative surgery is feasible, there are still disagreements about the scope of treatment or the type of treatment the patient chooses. In addition, there are still controversies about the most basic problems in system-assisted treatment, such as its mechanism of action and whether it is beneficial to patients. The determinants of local recurrence 1. Tumor-related factors: The study found two kinds of factors associated with local recurrence, namely the volume and histological type of the primary tumor. Data from the EORTC trial group and Amsterdam suggested that the primary tumor volume had no effect within the scope of indications for conservative treatment of breast cancer. Phase I and phase II tumor recurrence rates