[目的]观察辨证分型联合西药治疗晚期胃癌疗效。[方法]使用随机平行对照方法,将40例住院患者按病志号抽签法简单随机分为两组。对照组20例丝裂霉素,第1d,10mg/次,1次/d,静注;阿霉素,第1、8d,30mg/次,1次/d,静注;0.5g5-氟脲嘧啶+1000m L 5%葡萄糖,1次/d,持续5d,静滴。治疗组20例辨证分型:瘀毒内阻,失笑散(五灵脂、生蒲黄各10g,蒲公英、龙葵、藤梨根、铁树叶、仙鹤草各30g,当归、延胡索、桃仁、赤芍各10g,白屈菜、藕节、玉竹各20g);痰湿凝结,海藻玉壶汤合二陈汤(陈皮、郁金、半夏、海藻、浙贝母、昆布各10g,甘草6g,茯苓15g,生牡蛎30g,全瓜蒌30g);脾胃虚寒,附子理中汤(党参20g,半夏、白术、陈皮、制附子各10g,干姜、草豆蔻各6g,补骨脂、猪苓各15g);气血两亏,十全大补汤(黄芪、党参各30g,白术、当归、茯苓各15g,枸杞子、菟丝子各12g,川芎、熟地黄、枳壳、白芍各10g,肉桂6g);均1剂/d,水煎200m L,早晚口服;西药治疗同对照组。连续治疗30d为1疗程。观测临床症状、病灶、生存率、不良反应。连续治疗2疗程,判定疗效。[结果]治疗组完全缓解1例,部分缓解8例,稳定10例,无效1例,总有效率95.00%。对照组完全缓解0例,部分缓解4例,稳定10例,无效6例,总有效率70.00%。治疗组疗效优于对照组(P<0.05)。生存率治疗组改善优于对照组(P<0.05)。[结论]辨证分型联合西药治疗晚期胃癌疗效满意,无严重不良反应,值得推广。 [Objective] To observe the effect of syndrome differentiation and western medicine in treating advanced gastric cancer. [Methods] Using randomized parallel control method, 40 inpatients were randomly divided into two groups randomly according to the pathological code of lottery. The control group of 20 cases of mitomycin, the first day, 10mg / time, 1 / d, intravenous; doxorubicin, the first 1,8d, 30mg / time, Pyrimidine + 1000m L 5% glucose, 1 time / d, for 5d, intravenous infusion. Treatment group, 20 cases of syndrome differentiation type: blood stasis drug resistance, Lixiao San (Wulingzhi, Health Puhuang each 10g, dandelion, Solanum nigrum, iron leaves, Agrimony 30g, Angelica, Corydalis, Peach kernel, red Peony 10g, celandine, lotus root section, polygonatum each 20g); phlegm condensation, seaweed jug soup with two Chen Tang (tangerine peel, turmeric, Pinellia, seaweed, Fritillaria, kelp each 10g, licorice 6g , Poria 15g, raw oysters 30g, whole melon 蒌 30g); spleen Deficiency, aconite in the soup (Codonopsis 20g, Pinellia, Atractylodes, dried tangerine peel, 15g of Chinese Lingzhi, Chuanxiong, Rehmanniae, Citrus aurantium, white peony root of 10g, 15g of each of Polyporus umbellatus, 15g of each of Polyporus umbellatus, , Cinnamon 6g); 1 agent / d, decoction 200m L, morning and evening oral; Western medicine treatment with the control group. Continuous treatment of 30d for a course of treatment. Observation of clinical symptoms, lesions, survival rate, adverse reactions. Continuous treatment of 2 courses to determine the efficacy. [Results] The treatment group completely relieved in 1 case, partially relieved in 8 cases, stable in 10 cases, ineffective in 1 case, the total effective rate was 95.00%. The control group, complete remission in 0 cases, partial remission in 4 cases, stable in 10 cases, 6 cases, the total effective rate was 70.00%. The treatment group was better than the control group (P <0.05). Survival rate of treatment group improved better than the control group (P <0.05). [Conclusion] Syndrome differentiation combined with Western medicine in the treatment of advanced gastric cancer is satisfactory, with no serious adverse reactions, which deserves promotion.