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目的:根据对脑梗死患者的颈动脉超声检查结果,分析颈动脉粥样硬化与患者脑梗死之间的关联度,并进一步分析动脉粥样硬化的成因。方法:以湖南某医院脑梗死患者153例为样本(其中非进展性患者128例、进展性患者25例),另选非脑血管病患者50例作为对照组,进行颈动脉超声检查。结果:各组混合斑、硬斑及IMT增厚检出率在没有显著性差异(P>0.05),但动脉粥样硬化斑块检出率、软斑检出率有显著性差异(P<0.05);各组动脉狭窄比例明显不同(P<0.05);非进展性脑梗死组的梗死侧与非梗死侧斑块发生例数无显著性差异(P>0.05)。结论:动脉粥样硬化,很大程度上与年龄、性别、高血压、糖尿病、高密度脂蛋白胆固醇等因素有关,而颈动脉粥样硬化又是引发缺血性脑血管病的重要因素;进展性缺血脑卒中在很大程度上与动脉粥样硬化性质和狭窄程度有关,而粥样硬化的斑块性质及动脉狭窄程度,是脑血管病变是否处于高危状态的重要判断标准。
OBJECTIVE: To analyze the correlation between carotid atherosclerosis and cerebral infarction in patients with cerebral infarction based on the results of carotid ultrasonography and to further analyze the causes of atherosclerosis. Methods: A total of 153 patients with cerebral infarction in a hospital in Hunan Province were selected as samples (including 128 non-progressive patients and 25 progressive patients) and 50 patients with non-cerebrovascular disease as control group. Carotid ultrasonography was performed. Results: There was no significant difference in the detection rate of mixed plaque, plaque and IMT between groups (P> 0.05), but the detection rate of atherosclerotic plaque and the detection rate of soft spot were significantly different (P < 0.05). The proportions of arterial stenosis in each group were significantly different (P <0.05). There was no significant difference in the incidence of plaque between infarcted and non-infarcted sides in non-progressing cerebral infarction group (P> 0.05). Conclusion: Atherosclerosis is largely related to age, gender, hypertension, diabetes, high-density lipoprotein cholesterol and other factors, and carotid atherosclerosis is an important factor in ischemic cerebrovascular disease; progress Stroke is largely related to the nature of atherosclerosis and the degree of stenosis. The nature of atherosclerotic plaque and the degree of stenosis are important criteria for determining whether or not cerebrovascular disease is at high risk.