整合素是一类细胞黏附分子,它们是异二聚体糖蛋白,由非共价联系的α和β亚单位组成[1],在正常月经周期中,整合素在子宫内膜上皮细胞表面呈现时间及空间上的特异性表达。据报道α1,α4,β3整合素亚单位在腺上皮和腔上皮表达呈周期性,这三种整合素亚单位作为子宫内膜容受性的标志 Integrins are a class of cell adhesion molecules that are heterodimeric glycoproteins composed of non-covalently linked alpha and beta subunits [1]. During the normal menstrual cycle, integrins appear on the surface of endometrial epithelial cells Time and space-specific expression. It is reported that α1, α4, β3 integrin subunits in the gland epithelium and luminal epithelial expression was periodic, these three integrin subunits as a marker of endometrial receptivity