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目的分析中山市2003—2012年流行性脑脊髓膜炎(流脑)的流行特征和菌群分布特征,为制定中山市流脑防制策略提供科学依据。方法采用描述性流行病学方法对中山市2003—2012年流脑疫情资料和个案调查资料进行分析。结果 2003—2012年中山市共报告流脑病例14例,年平均发病为0.05/10万。14例病例中4月龄3例、6岁1例、>17岁10例;男性7例,女性7例;病例发病时间分别1、2、3、4、5、10、12月,其中3月份报告病例数最多为6例,其他月份报告病例数分别为1~2例。14例病例的脑脊液或血液样本均培养出脑膜炎奈瑟菌,其中A群7例,B群、C群、W135群各2例,A+B群混合感染1例。结论中山市近年流脑发病率控制在较低的水平,今后应继续加强对流脑菌群的监测,根据流行型别及时调整流脑疫苗免疫策略。
Objective To analyze epidemiological characteristics and distribution of epidemic cerebrospinal meningitis (MCI) in Zhongshan City from 2003 to 2012, and to provide scientific basis for the establishment of meningococcal control strategy in Zhongshan City. Methods Descriptive epidemiological methods were used to analyze the epidemiological data and cases of epidemic encephalitis in Zhongshan City from 2003 to 2012. Results From 2003 to 2012, Zhongshan City reported a total of 14 cases of meningitis cases, with an average annual incidence of 0.05 / 100,000. 14 cases were 4 months old in 3 cases, 6 years old in 1 case and> 17 years old in 10 cases. There were 7 males and 7 females. The onset time was 1, 2, 3, 4, 5, 10 and 12 months respectively The number of reported cases in the month was up to 6 cases and the number of reported cases in other months was 1 to 2 cases respectively. Neisseria meningitidis was cultured in cerebrospinal fluid or blood samples of 14 cases, including 7 cases in group A, 2 cases in group B, group C and group W135, and 1 case in group A + B. Conclusion The incidence of meningitis in Zhongshan City in recent years is controlled at a relatively low level. In the future, the surveillance of meningococcal flora should be strengthened and the immunization strategy of meningococcal vaccine should be adjusted in time according to the prevalence.