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本文叙述了一种测定原料药和制剂中氯霉素及其衍生物的分光光度法.该法基于氯霉素及其衍生物经碱水解后,在酸性介质中将钼酸铵还原成钼蓝,于670nm处测定吸收度.方法简易且灵敏准确.作者对
This paper describes a spectrophotometric method for the determination of chloramphenicol and its derivatives in pharmaceutical raw materials and preparations.The method is based on the chloramphenicol and its derivatives after alkali hydrolysis, the ammonium molybdate is reduced to molybdenum blue in an acidic medium , Measured at 670nm absorbance method is simple and sensitive and accurate